St. Louis Trauma nurse Casey McDonough thinks her life is interesting enough. Her best friend still drops acid, her ex-husband is a cross-dressing psychiatrist, and her mother has turned the third floor of the family home into the Chapel of Eternal Vigilance. But things begin to go wrong fast when OB/Gyn Dr. Dale Hunsacker arrives on the scene, because Casey suspects that the handsome, charismatic doctor is actually a serial killer. And the only one who takes her seriously, is Hunsacker himself. Caught in a spiral of suspicion and intimidation, Casey works with ex-Marine, ex-Jesuit homicide sergeant Jack Scanlan to help her prove that a monster walks the halls of her hospital.